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For first time users with vaginal dryness and painful sex. Starting from the mild Silk formula then move up to the Silver formula and finally the strong Gold formula. For women after menopause but younger than 65 and have vaginal dryness and atrophy the Silk formula would be a good choice. For women 65 or older or had cancer treatment with severe vaginal atrophy use NeuEve Cream for 1 month before using NeuEVe Silk. Ease vaginal dryness painful sex and vaginal atrophy. Works well when combined with the NeuEve cream. Long lasting effect. If you cannot tolerate the side effect of hormones you should try NeuEve. Hormone free. All natural green. Patented formula invented by a gynecologist.